Santos, originally Portuguese or Spanish for Saints (singular Santo), is a common surname in Spanish and Portuguese. Sometimes it can be the final part of a given name, generally preceded by the particle dos or de los (of the, meaning of the Saints, as in Miguel dos Santos, Michael of the Saints). It is a name associated with a great number of different people:
- Santos (Sante Pucello), Italian DJ
- Álvaro Santos, Brazilian footballer
- Ahmed Santos, Mexican newspaper columnist and former boxer
- Ahmed Santos, Phillipino convert to Islam and militant.
- Alberto Santos-Dumont, Brazilian aviation pioneer
- Alessandro dos Santos, Brazilian-Japanese footballer
- Antonio da Costa Santos, Brazilian architect and politician
- António dos Santos Ramalho Eanes, Portuguese general and politician
- Ary dos Santos, Portuguese poet
- Conrad Santos, Canadian politician
- Cristiano Ronaldo dos Santos Aveiro, Portuguese footballer
- Daniel Santos, Puerto Rican boxer
- Daniel Santos, Puerto Rican singer and composer
- Djalma Santos, Brazilian footballer.
- Domingo Santos, Spanish writer
- Domitila, Marchioness of Santos, Brazilian noblewoman and the mistress of Emperor Pedro I of Brazil
- Enrique Santos Discépolo, Argentinian musician
- Erik Ramos Santos, Filipino singer.
- Fausto dos Santos, Brazilian footballer.
- Felipe Juan Pablo Alfonso de Todos los Santos de Borbón y de Grecia, heir to the Spanish throne
- Fernando Santos, Brazilian footballer
- Fernando da Piedade Dias dos Santos, Angolan politician
- Fernando Victor Emanuel Costa Santos, Portuguese football manager
- Georges Santos, French-born, Cape Verdean footballer
- Giovani dos Santos, Mexican footballer
- Hélio de Oliveira Santos, Brazilian physician and politician
- Joe Santos, American actor
- Joly Braga Santos, Portuguese composer and conductor
- José Eduardo dos Santos, Angolan politician
- José Santos Guardiola, Honduran politician
- José Santos Zelaya, Nicaraguan politician
- José dos Santos Ferreira, Portuguese-Macanese writer
- Jovino Santos-Neto, Brazilian musician
- Judy Ann Santos, Filipino actress
- Leslie George Santos, Hong Kong footballer
- Lucélia Santos, Brazilian actress, director and producer
- Lúcia dos Santos, known as Sister Lúcia of Jesus, Portuguese Roman Catholic Carmelite nun and seer of Our Lady of Fatima
- Manuel António dos Santos, Portuguese politician
- Matt Santos, fictional character on the American television show The West Wing
- Mayra Santos-Febres, Puerto-Rican writer
- Nelson Pereira dos Santos, Brazilian movie director
- Nílton Santos, Brazilian football player
- Pablo Santos, Mexican actor
- Paulo Jorge dos Santos Futre, Portuguese football player
- Artur Carlos Maurício Pestana dos Santos, known as Pepetela, Angolan writer
- Ricardo Santos, Brazilian beach volleyball player
- Roberto Santos, Brazilian film director
- Rufino Jiao Santos, Filipino Archbishop of Manila
- Santos Acosta, Colombian general and political figure
- Santos Benavides, American military
- Santos Ortega, American actor
- Vicente Abad Santos, Justice of the Supreme Court of the Philippines
- Victor Irving Santos, American baseball player
- Vilma Santos, Filipino actress
- José Manuel Cerqueira Afonso dos Santos, known as Zeca Afonso, Portuguese singer, composer and poet
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