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Sertraline hydrochloride (Zoloft, Lustral) is an antidepressant of the
selective serotonin reuptake inhibitor (SSRI) class. It was introduced to
the market by Pfizer in 1991. Sertraline is primarily used to treat
clinical depression in adult outpatients as well as obsessive-compulsive,
panic and social anxiety disorders in both adults and children. Sertraline
shares the common side effects and contraindications with other members of
SSRI class; however, it does not cause weight gain. Controversy and legal
actions have resulted from the suspicion that sertraline, similarly to
other antidepressants, may increase the risk of suicide. In 2006 it was the
most prescribed antidepressant on the U.S. retail market with 28,060,000
prescriptions.The sertraline prescriptions were calculated as a total of
prescriptions for Zoloft and generic Sertraline using data from the charts
for generic and brand name drugs, see: and Drug
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