Sisco could refer to the following people: · Kristina Sisco, an American actress · Karen Sisco, a fictional United States Marshal created by novelist Elmore Leonard, or the TV series of the same name. She also appears in the film Out of Sight Sisko could refer to the following fictional characters from the television series, Deep Space Nine: · Benjamin Sisko · Jake Sisko · Jennifer Sisko · Joseph Sisko Sisko may also refer to Sisqó, an R&B performer and the lead singer of Dru Hill

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